Article
Valve-sparing aortic root replacement in Loeys-Dietz syndrome.
The Annals of thoracic surgery - 1 Aug 2011
Patel Nishant D, Arnaoutakis George J, George Timothy J, Allen Jeremiah G, Alejo Diane E, Dietz Harry C, Cameron Duke E, Vricella Luca A
Abstract excerpt
BACKGROUND: Loeys-Dietz syndrome (LDS) is a recently recognized aggressive aortic disorder characterized by root aneurysm, arterial tortuosity, hypertelorism, and bifid uvula or cleft palate. The results of prophylactic root replacement using valve-sparing procedures (valve-sparing root replacement [VSRR]) in patients with LDS is not known. METHODS: We reviewed all patients with clinical and genetic (transforming...
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