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Article

AKT1 moderation of cannabis-induced cognitive alterations in psychotic disorder.

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Nov 2011

van Winkel Ruud, van Beveren Nico J M, Simons Claudia

Abstract excerpt

Genetic variation in AKT1 may be associated with sensitivity to the psychotomimetic effects of cannabis as well as with increased risk for psychotic disorder following cannabis use. Investigation of the effect of this interaction on relevant intermediate phenotypes for psychosis, such as cognition, may help to clarify the underlying mechanism. Thus, verbal memory (visually presented Word Learning Task), sustained...

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Identifiers

PMID: 21775978
DOI: 10.1038/npp.2011.141
PMCID: PMC3194079

Genes

AKT1

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