Article
Limitations of spoligotyping and variable-number tandem-repeat typing for molecular tracing of Mycobacterium bovis in a high-diversity setting.
Journal of clinical microbiology - 1 Sept 2011
Rodriguez-Campos Sabrina, Aranaz Alicia, de Juan Lucía, Sáez-Llorente José Luis, Romero Beatriz, Bezos Javier, Jiménez Antonio, Mateos Ana, Domínguez Lucas
Abstract excerpt
This study describes the attempt to trace the first Mycobacterium bovis outbreak in alpacas (Lama pacos) in Spain by spoligotyping and variable-number tandem-repeat (VNTR) analysis. Due to high genotype diversity, no matching source was identified, but local expansion of a clonal group was found and its significance for molecular tracing is discussed.
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