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Article

Clinical manifestations of mutations in RAS and related intracellular signal transduction factors.

Current opinion in pediatrics - 1 Aug 2011

Zenker Martin

Abstract excerpt

PURPOSE OF REVIEW: Recent advances in molecular genetic research have led to the definition of the new group of genetic syndromes, the RAS-mitogen-activated protein kinase (MAPK) pathway disorders or 'RASopathies'. They comprise Noonan syndrome and related disorders (cardio-facio-cutaneous and Costello syndromes), as well as neurofibromatosis type 1. This review summarizes the recent literature with a special...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21750428
DOI: 10.1097/MOP.0b013e32834881dd

Genes

CBL
NRAS

Provenance

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