Article
The JAK2V617F allele burden and STAT3- and STAT5 phosphorylation in myeloproliferative neoplasms: early prefibrotic myelofibrosis compared with essential thrombocythemia, polycythemia vera and myelofibrosis.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Aug 2011
Risum Malene, Madelung Ann, Bondo Henrik, Bzorek Michael, Kristensen Michael Holmsgaard, Stamp Inger Merete, Hasselbalch Hans Carl
Abstract excerpt
Early prefibrotic myelofibrosis (early PMF) is a diagnosis that clinically and histologically mimic essential thrombocythemia (ET), but is important to distinguish from ET, polycythemia vera (PV) and primary myelofibrosis (PMF) due to its different prognosis and clinical evolution. In this study, we assessed the allele burden of JAK2V617F in bone marrow biopsies from patients with these chronic myeloproliferative...
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