Article
Gastrointestinal microbiome signatures of pediatric patients with irritable bowel syndrome.
Gastroenterology - 1 Nov 2011
Saulnier Delphine M, Riehle Kevin, Mistretta Toni-Ann, Diaz Maria-Alejandra, Mandal Debasmita, Raza Sabeen, Weidler Erica M, Qin Xiang, Coarfa Cristian, Milosavljevic Aleksandar, Petrosino Joseph F, Highlander Sarah, Gibbs Richard, Lynch Susan V, Shulman Robert J, Versalovic James
Abstract excerpt
BACKGROUND & AIMS: The intestinal microbiomes of healthy children and pediatric patients with irritable bowel syndrome (IBS) are not well defined. Studies in adults have indicated that the gastrointestinal microbiota could be involved in IBS. METHODS: We analyzed 71 samples from 22 children with IBS (pediatric Rome III criteria) and 22 healthy children, ages 7-12 years, by 16S ribosomal RNA gene sequencing, with...
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