Article
No increase in the expression of key unfolded protein response genes in HCV genotype 3 patients with severe steatosis.
Virus research - 1 Sept 2011
Congiu Mario, Ryan Marno C, Desmond Paul V
Abstract excerpt
Although hepatic steatosis is common in patients infected with HCV, the mechanisms leading to cellular triglyceride retention are obscure. A role for the Unfolded Protein Response (UPR) has been postulated, either through its activation or dysfunction. In this study we set out to investigate the...
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