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Article

Transforming growth factor signalling: a common pathway in pulmonary arterial hypertension and systemic sclerosis.

International journal of clinical practice. Supplement - 1 Aug 2011

Hatton N, Frech T, Smith B, Sawitzke A, Scholand M B, Markewitz B

Abstract excerpt

Pulmonary arterial hypertension (PAH) is a clinical condition characterised by the presence of precapillary pulmonary hypertension (PH). Included within the subcategorisation of PAH are heritable (HPAH) and PAH associated various conditions (APAH) including systemic sclerosis (SSc). The pathogenesis of HPAH and SSc has been linked to both a genetic predisposition and epigenetic factors. TGF-β superfamily...

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Share to Familial Primary Pulmonary Hypertension
Share to Hypertension, Pulmonary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Receptors, Transforming Growth Factor beta

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Share to Scleroderma, Systemic

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Source

Identifiers

PMID: 21736678
DOI: 10.1111/j.1742-1241.2011.02726.x

Genes

PAH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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