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Article

Functional splicing assay of DSPP mutations in hereditary dentin defects.

Oral diseases - 1 Oct 2011

Lee K-E, Lee S-K, Jung S-E, Lee Zh, Kim J-W

Abstract excerpt

OBJECTIVE: Dentin sialophosphoprotein (DSPP) gene mutations have been identified in isolated hereditary dentin defects; however, the genotype-phenotype correlations are poorly understood. We performed in vitro splicing assays to test the hypothesis that DSPP mutations in splice junctions as well as proposed missense/nonsense mutations experimentally result in aberrant pre-mRNA splicing. MATERIALS AND METHODS: The...

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Source

Identifiers

PMID: 21736673
DOI: 10.1111/j.1601-0825.2011.01825.x

Genes

DSPP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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