Article
Severe combined immunodeficiency in Greek children over a 20-year period: rarity of γc-chain deficiency (X-linked) type.
Journal of clinical immunology - 1 Oct 2011
Michos Athanasios, Tzanoudaki Marianna, Villa Anna, Giliani Silvia, Chrousos George, Kanariou Maria
Abstract excerpt
Severe combined immunodeficiencies (SCID) are a heterogeneous group of genetic disorders characterized by a blockade or impairment of both cellular and humoral immunity. Several epidemiological studies in different geographic areas have shown that the most common type of SCID affecting almost half of these patients is the X-linked common γ-chain (γ(c)) deficiency. The objective of the study was to document the...
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