Article
Harnessing endogenous growth factor activity modulates stem cell behavior.
Integrative biology : quantitative biosciences from nano to macro - 1 Aug 2011
Hudalla Gregory A, Kouris Nicholas A, Koepsel Justin T, Ogle Brenda M, Murphy William L
Abstract excerpt
The influence of specific serum-borne biomolecules (e.g. heparin) on growth factor-dependent cell behavior is often difficult to elucidate in traditional cell culture due to the random, non-specific nature of biomolecule adsorption from serum. We hypothesized that chemically well-defined cell culture substrates could be used to study the influence of sequestered heparin on human mesenchymal stem cell (hMSC)...
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