Article
Assessment of copy number status of chromosomes 6 and 11 by FISH provides independent prognostic information in primary melanoma.
The American journal of surgical pathology - 1 Aug 2011
North Jeffrey P, Vetto John T, Murali Rajmohan, White Kevin P, White Clifton R, Bastian Boris C
Abstract excerpt
Melanoma incidence has been rising steadily for decades, whereas mortality rates have remained flat. This type of discordant pattern between incidence and mortality has been linked to diagnostic drift in cancers of the thyroid, breast, and prostate. Ancillary tests, such as fluorescent in situ hybridization (FISH), are now being used to help differentiate melanomas from melanocytic nevi. Multicolor FISH has been...
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