Alleles at the PRB3 locus coding for a disulfide-bonded human salivary proline-rich glycoprotein (Gl 8) and a null in an Ashkenazi Jew.

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Article

Alleles at the PRB3 locus coding for a disulfide-bonded human salivary proline-rich glycoprotein (Gl 8) and a null in an Ashkenazi Jew.

American journal of human genetics - 1 Oct 1990

Azen E A, Minaguchi K, Latreille P, Kim H S

Abstract excerpt

From electrophoretic analysis, we identified in the saliva of an Ashkenazi Jew a disulfide-bonded major glycoprotein variant (Gl 8) that is a product of the proline-rich protein (PRP) locus PRB3. A previous study of this variant protein misidentified it as Pa 2 and as a product of a different PRP locus. The other PRB3 allele in this individual is an apparent null. To identify the mutations, we sequenced the...

Topics

Alleles
Amino Acid Sequence
Base Sequence
Cloning, Molecular
DNA Mutational Analysis
Disulfides
Electrophoresis, Polyacrylamide Gel
Exons
Frameshift Mutation
Gene Expression
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Jews

Male

Molecular Sequence Data

Peptides

Peroxidase

Phenotype

Proline

Source

Open in PubMed Open full text

Identifiers

PMID: 2171329
PMCID: PMC1683781

Genes

PRB3
PRH1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2171329-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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