Article
Balanced into array: genome-wide array analysis in 54 patients with an apparently balanced de novo chromosome rearrangement and a meta-analysis.
European journal of human genetics : EJHG - 1 Nov 2011
Feenstra Ilse, Hanemaaijer Nicolien, Sikkema-Raddatz Birgit, Yntema Helger, Dijkhuizen Trijnie, Lugtenberg Dorien, Verheij Joke, Green Andrew, Hordijk Roel, Reardon William, Vries Bert de, Brunner Han, Bongers Ernie, Leeuw Nicole de, van Ravenswaaij-Arts Conny
Abstract excerpt
High-resolution genome-wide array analysis enables detailed screening for cryptic and submicroscopic imbalances of microscopically balanced de novo rearrangements in patients with developmental delay and/or congenital abnormalities. In this report, we added the results of genome-wide array analysis in 54 patients to data on 117 patients from seven other studies. A chromosome imbalance was detected in 37% of all...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.