Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

High-sensitivity CRP discriminates HNF1A-MODY from other subtypes of diabetes.

Diabetes care - 1 Aug 2011

McDonald Tim J, Shields Beverley M, Lawry Jane, Owen Katharine R, Gloyn Anna L, Ellard Sian, Hattersley Andrew T

Abstract excerpt

OBJECTIVE: Maturity-onset diabetes of the young (MODY) as a result of mutations in hepatocyte nuclear factor 1-α (HNF1A) is often misdiagnosed as type 1 diabetes or type 2 diabetes. Recent work has shown that high-sensitivity C-reactive protein (hs-CRP) levels are lower in HNF1A-MODY than type 1 diabetes, type 2 diabetes, or glucokinase (GCK)-MODY. We aim to replicate these findings in larger numbers and other...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to C-Reactive Protein
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to CRP gene

Share to GCK gene

Share to Hepatocyte Nuclear Factor 1-alpha

Share to Mutation

Share to Pancreatic function and diabetes

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 21700917
DOI: 10.2337/dc11-0323
PMCID: PMC3142017

Genes

CRP
GCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

High-sensitivity CRP discriminates HNF1A-MODY from other subtypes of diabetes.PMID 21700917Read ↗

Assessment of high-sensitivity C-reactive protein levels as diagnostic discriminator of maturity-onset diabetes of the young due to HNF1A mutations.Semantic proximity Read ↗

A large multi-centre European study validates high-sensitivity C-reactive protein (hsCRP) as a clinical biomarker for the diagnosis of diabetes subtypes.Semantic proximity Read ↗

Update on clinical screening of maturity-onset diabetes of the young (MODY)Semantic proximity Read ↗

An alternative approach using hs-CRP levels and age of onset in diagnostics of HNF1A-MODY.Semantic proximity Read ↗

Plasma Fucosylated Glycans and C-Reactive Protein as Biomarkers of HNF1A-MODY in Young Adult–Onset Nonautoimmune DiabetesSemantic proximity Read ↗

Insights from basic adjunctive examinations of GCK-MODY, HNF1A-MODY, and type 2 diabetes: A systemic review and meta-analysis.Semantic proximity Read ↗

Frequency and Characteristics of MODY 1 (HNF4A Mutation) and MODY 5 (HNF1B Mutation): Analysis From the DPV DatabaseSemantic proximity Read ↗

Systematic assessment of etiology in adults with a clinical diagnosis of young-onset type 2 diabetes is a successful strategy for identifying maturity-onset diabetes of the young.Semantic proximity Read ↗

Using highly sensitive C-reactive protein measurement to diagnose MODY in a family with suspected type 2 diabetes.Semantic proximity Read ↗

HNF1A：From Monogenic Diabetes to Type 2 Diabetes and Gestational Diabetes Mellitus.Semantic proximity Read ↗

Spectrum of HNF1A and GCK mutations in Canadian families with maturity-onset diabetes of the young (MODY).Semantic proximity Read ↗

Mutations in HNF1A result in marked alterations of plasma glycan profile.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.