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Article

Investigating the pathogenic role of PADI4 in oesophageal cancer.

International journal of biological sciences - 1 Jan 2011

Chang Xiaotian, Hou Xiuli, Pan Jihong, Fang Kehua, Wang Lin, Han Jinxiang

Abstract excerpt

PADI4 post-translationally converts peptidylarginine to citrulline. PADI4 can disrupt the apoptotic process via the citrullination of histone H3 in the promoter of p53-target genes. The current study focused on PADI4 expression in various subtypes of oesophageal carcinoma (EC) by immunohistochemistry, western blotting and real time PCR. The study also investigated the effect of bile acid deoxycholate (DCA) on...

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Source

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Identifiers

PMID: 21698003
DOI: 10.7150/ijbs.7.769
PMCID: PMC3119849

Genes

PADI4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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