Article
Low-dose gefitinib treatment for patients with advanced non-small cell lung cancer harboring sensitive epidermal growth factor receptor mutations.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Aug 2011
Satoh Hironori, Inoue Akira, Kobayashi Kunihiko, Maemondo Makoto, Oizumi Satoshi, Isobe Hiroshi, Gemma Akihiko, Saijo Yasuo, Yoshizawa Hirohisa, Hagiwara Koichi, Nukiwa Toshihiro
Abstract excerpt
INTRODUCTION: Although standard schedule of gefitinib was the administration of 250 mg tablet every day, many patients need dose reduction because of toxicities. However, the efficacy of such low-dose gefitinib for patients with epidermal growth factor receptor-mutated non-small cell lung cancer has rarely been evaluated. METHODS: A post hoc comparison of the efficacy (response rate and survival) in patients...
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