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Decreased expression of surfactant protein D mRNA in human lungs in fatal cases of H5N1 avian influenza

15 Jun 2011

Abstract excerpt

Microarray analysis of gene expression profile of lungs from two fatal H5N1 influenza cases identified 3,435 genes with higher than twofold changes in mRNA levels as compared to those of normal lung. One thousand nineteen genes and 2,416 genes were up-regulated and down-regulated commonly, respectively. Gene ontology analysis identified several ontology terms with significant association with these genes, most of...

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PMID: 21678446
DOI: 10.1002/jmv.22105

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