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Effect of stem cell source on outcomes after unrelated donor transplantation in severe aplastic anemia

16 Jun 2011

Abstract excerpt

Outcome after unrelated donor bone marrow (BM) transplantation for severe aplastic anemia (SAA) has improved, with survival rates now approximately 75%. Increasing use of peripheral blood stem and progenitor cells (PBPCs) instead of BM as a graft source prompted us to compare outcomes of PBPC and BM transplantation for SAA. We studied 296 patients receiving either BM (n = 225) or PBPC (n = 71) from unrelated...

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PMID: 21677312
DOI: 10.1182/blood-2011-05-354001

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