Article
Prevalence, distribution and evolutionary significance of the IS629 insertion element in the stepwise emergence of Escherichia coli O157:H7.
BMC microbiology - 14 Jun 2011
Rump Lydia V, Fischer Markus, Gonzalez-Escalona Narjol
Abstract excerpt
BACKGROUND: Insertion elements (IS) are known to play an important role in the evolution and genomic diversification of Escherichia coli O157:H7 lineages. In particular, IS629 has been found in multiple copies in the E. coli O157:H7 genome and is one of the most prevalent IS in this serotype. It was recently shown that the lack of O157 antigen expression in two O rough E. coli O157:H7 strains was due to IS629...
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