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Article

Hereditary leukonychia, or porcelain nails, resulting from mutations in PLCD1.

American journal of human genetics - 10 Jun 2011

Kiuru Maija, Kurban Mazen, Itoh Munenari, Petukhova Lynn, Shimomura Yutaka, Wajid Muhammad, Christiano Angela M

Abstract excerpt

Hereditary leukonychia (porcelain nails or white nails) is a rare nail disorder with an unknown genetic basis. To identify variants in a gene underlying this phenotype, we identified four families of Pakistani origin showing features of hereditary leukonychia. All 20 nails of each affected individual were chalky and white in appearance, consistent with total leukonychia, with no other cutaneous, appendageal, or...

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Source

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Identifiers

PMID: 21665001
DOI: 10.1016/j.ajhg.2011.05.014
PMCID: PMC3113240

Genes

PLCD1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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