Article
On the relation between the Eigen model and the asexual Wright-Fisher model.
Bulletin of mathematical biology - 1 Jan 2012
Musso Fabio
Abstract excerpt
We show that the Eigen model and the asexual Wright-Fisher model can be obtained as two different limit cases of a single stochastic model. This result is used to enlighten the mathematical similarities and differences among these two models.The two key concepts introduced with the Eigen model, the error threshold and the quasispecies, are not invalidated by these differences, so that they are naturally present...
Topics
- Genetics, Population
- Models, Genetic
- Models, Statistical
- Mutation
- Ploidies
- Selection, Genetic
- Stochastic Processes