Article
False-negative results using Neisseria gonorrhoeae porA pseudogene PCR - a clinical gonococcal isolate with an N. meningitidis porA sequence, Australia, March 2011.
Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin - 26 May 2011
Whiley D M, Limnios A, Moon N J, Gehrig N, Goire N, Hogan T, Lam A, Jacob K, Lambert S B, Nissen M D, Sloots T P
Abstract excerpt
The gonococcal porA pseudogene is a popular target for in-house Neisseria gonorrhoeae PCR methods. With this study we present two novel findings: the first case of an N. gonorrhoeae porA pseudogene PCR false-negative result caused by sequence variation, and in the same organism, the first description of a clinical N. gonorrhoeae strain harbouring an N. meningitidis porA sequence.
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