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Article

Comparative genomics of four closely related Clostridium perfringens bacteriophages reveals variable evolution among core genes with therapeutic potential.

BMC genomics - 1 Jun 2011

Oakley Brian B, Talundzic Eldin, Morales Cesar A, Hiett Kelli L, Siragusa Gregory R, Volozhantsev Nikolay V, Seal Bruce S

Abstract excerpt

BACKGROUND: Because biotechnological uses of bacteriophage gene products as alternatives to conventional antibiotics will require a thorough understanding of their genomic context, we sequenced and analyzed the genomes of four closely related phages isolated from Clostridium perfringens, an important agricultural and human pathogen. RESULTS: Phage whole-genome tetra-nucleotide signatures and proteomic tree...

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PMID: 21631945
DOI: 10.1186/1471-2164-12-282
PMCID: PMC3118219

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

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