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Article

Systems mapping: how to improve the genetic mapping of complex traits through design principles of biological systems.

BMC systems biology - 27 May 2011

Wu Rongling, Cao Jiguo, Huang Zhongwen, Wang Zhong, Gai Junyi, Vallejos Eduardo

Abstract excerpt

BACKGROUND: Every phenotypic trait can be viewed as a "system" in which a group of interconnected components function synergistically to yield a unified whole. Once a system's components and their interactions have been delineated according to biological principles, we can manipulate and engineer functionally relevant components to produce a desirable system phenotype. RESULTS: We describe a conceptual framework...

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Identifiers

PMID: 21615967
DOI: 10.1186/1752-0509-5-84
PMCID: PMC3127792

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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