Article
Active regulation of receptor ratios controls integration of quorum-sensing signals in Vibrio harveyi.
Molecular systems biology - 24 May 2011
Teng Shu-Wen, Schaffer Jessica N, Tu Kimberly C, Mehta Pankaj, Lu Wenyun, Ong N P, Bassler Bonnie L, Wingreen Ned S
Abstract excerpt
Quorum sensing is a chemical signaling mechanism used by bacteria to communicate and orchestrate group behaviors. Multiple feedback loops exist in the quorum-sensing circuit of the model bacterium Vibrio harveyi. Using fluorescence microscopy of individual cells, we assayed the activity of the quorum-sensing circuit, with a focus on defining the functions of the feedback loops. We quantitatively investigated the...
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