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Article

Plasma homocysteine levels, methylene tetrahydrofolate reductase polymorphisms, and the risk of thromboembolism in children.

Journal of pediatric hematology/oncology - 1 Jul 2011

Nahar Akash, Sabo Cynthia, Chitlur Meera, Ravindranath Yaddanapudi, Lusher Jeanne, Rajpurkar Madhvi

Abstract excerpt

INTRODUCTION: Hyperhomocystenemia (HHcy) is a risk factor for thrombosis in adults. Polymorphisms in methylene tetrahydrofolate reductase (MTHFR) enzyme may cause HHcy. Data on their role in pediatric thromboembolism (TE) are sparse. MATERIALS AND METHODS: Charts of patients from 1989 to 2007, with documented TE, were reviewed. Homocysteine (Hcy) levels were defined both as per the adult normal range and the...

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Identifiers

PMID: 21602719
DOI: 10.1097/MPH.0b013e318219324f

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MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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