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Article

Diabetes and neurodegeneration in Wolfram syndrome: a multicenter study of phenotype and genotype.

Diabetes care - 1 Jul 2011

Rohayem Julia, Ehlers Christian, Wiedemann Bärbel, Holl Reinhard, Oexle Konrad, Kordonouri Olga, Salzano Giuseppina, Meissner Thomas, Burger Walter, Schober Edith, Huebner Angela, Lee-Kirsch Min Ae

Abstract excerpt

OBJECTIVE: To describe the diabetes phenotype in Wolfram syndrome compared with type 1 diabetes, to investigate the effect of glycemic control on the neurodegenerative process, and to assess the genotype-phenotype correlation. RESEARCH DESIGN AND METHODS: The clinical data of 50 patients with Wolfram syndrome-related diabetes (WSD) were reviewed and compared with the data of 24,164 patients with type 1 diabetes....

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21602428
DOI: 10.2337/dc10-1937
PMCID: PMC3120194

Genes

WFS1

Provenance

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