Article
Myocardial gene expression of microRNA-133a and myosin heavy and light chains, in conjunction with clinical parameters, predict regression of left ventricular hypertrophy after valve replacement in patients with aortic stenosis.
Heart (British Cardiac Society) - 1 Jul 2011
Villar Ana V, Merino David, Wenner Mareike, Llano Miguel, Cobo Manuel, Montalvo Cecilia, García Raquel, Martín-Durán Rafael, Hurlé Juan M, Hurlé María A, Nistal J Francisco
Abstract excerpt
BACKGROUND: Left ventricular (LV) reverse remodelling after valve replacement in aortic stenosis (AS) has been classically linked to the hydraulic performance of the replacement device, but myocardial status at the time of surgery has received little attention. OBJECTIVE: To establish predictors of LV mass (LVM) regression 1 year after valve replacement in a surgical cohort of patients with AS based on...
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