Article
Changes in clonal growth, immunophenotype, and morphology during a follow-up study of an acute lymphoblastic leukemia.
Haematology and blood transfusion - 1 Jan 1990
Reichle A, Volkmann M, Pachmann K, Diddens H, Emmerich B, Rastetter J
Abstract excerpt
Cells of a 21-year-old patient with acute lymphatic leukemia were analyzed for morphology and immunophenotype and for genotype consecutively during the course of disease. Initial therapy with the BMFT-ALL protocol (Bundesministerium für Forschung und Technologie) reduced leukemic cells only marginally. The following high-dose Ara-C, mitoxantrone (HAM) chemotherapy led to a cell reduction of 75% and to a drastic...
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