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Article

Profound changes in drug metabolism enzymes and possible effects on drug therapy in neonates and children.

Expert opinion on drug metabolism & toxicology - 1 Aug 2011

de Wildt Saskia N

Abstract excerpt

INTRODUCTION: There are profound changes that take place in drug metabolism enzymes during fetal and postnatal development. These changes may significantly impact drug therapy in children. AREAS COVERED: A combination of focused and comprehensive literature searches using PubMed and reference lists (from inception to 7 November 2009) is undertaken to identify reports on in vitro and in vivo development of drug...

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PMID: 21548840
DOI: 10.1517/17425255.2011.577739

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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