Article
Oligoclonal immunoglobulin heavy chain gene rearrangement in a childhood immunoblastic lymphoma. Presentation as a polyphenotypic atypical lymphoproliferative reaction.
American journal of clinical pathology - 1 Feb 1990
Whitten R O, Zutter M, Iaci-Hall J, Odell M, Kidd P
Abstract excerpt
The authors describe a diagnostically difficult case of childhood lymphoma that presented as an atypical polyphenotypic lymphoproliferative reaction. Initial immunophenotyping revealed the presence of IgG, IgA, kappa, and lambda within the neoplastic lymphocytes. The patient had circulating plasm...
Topics
- Blotting, Southern
- Child
- Clone Cells
- DNA, Viral
- Diagnosis, Differential
- Female
- Gene Rearrangement, beta-Chain T-Cell Antigen Receptor
- Herpesvirus 4, Human
- Humans
- Immunoglobulin Heavy Chains
- Lymphoma, Non-Hodgkin
- Lymphoproliferative Disorders
- Phenotype