Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic modifiers of liver injury in hereditary liver disease.

Seminars in liver disease - 1 May 2011

Ala Aftab, Schilsky Michael

Abstract excerpt

The genetic background of patients with liver diseases modulates hepatic injury, with some individuals being predisposed to better defenses and regenerative capacity. In this review, we focus our description of this phenomenon on inherited disorders affecting the liver, with a particular emphasis on Wilson disease (WD), genetic hemochromatosis, and α-1 anti-trypsin disease (A1-AT). Wide variations in the clinical...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to alpha 1-Antitrypsin
Share to alpha 1-Antitrypsin Deficiency
Share to Cation Transport Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Copper-Transporting ATPases

Share to Hemochromatosis

Share to Hemochromatosis Protein

Share to Hepatolenticular Degeneration

Share to Heredity

Source

Identifiers

PMID: 21538285
DOI: 10.1055/s-0031-1276648

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic modifiers of liver injury in hereditary liver disease.PMID 21538285Read ↗

Inherited metabolic disease of the liver.Semantic proximity Read ↗

Inherited metabolic disease of the liver.Semantic proximity Read ↗

Genetic and environmental modifiers of Wilson disease.Semantic proximity Read ↗

Inherited metabolic liver disease.Semantic proximity Read ↗

Genetic mechanisms and modifying factors in hereditary hemochromatosis.Semantic proximity Read ↗

[Hereditary liver diseases].Semantic proximity Read ↗

[Factors influencing the clinical phenotype of hepatolenticular degeneration].Semantic proximity Read ↗

Recent advance in the molecular genetics of Wilson disease and hereditary hemochromatosis.Semantic proximity Read ↗

Modifying factors and phenotypic diversity in Wilson's disease.Semantic proximity Read ↗

Metals and the liver.Semantic proximity Read ↗

Impaired hepcidin expression in alpha-1-antitrypsin deficiency associated with iron overload and progressive liver diseaseSemantic proximity Read ↗

[Hereditary hemochromatosis, alpha-1-antitrypsin deficiency and Wilson's disease. Pathogenesis, clinical findings and pathways to diagnosis].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.