Article
An unusual splice defect in the mitofusin 2 gene (MFN2) is associated with degenerative axonopathy in Tyrolean Grey cattle.
PloS one - 15 Apr 2011
Drögemüller Cord, Reichart Ursula, Seuberlich Torsten, Oevermann Anna, Baumgartner Martin, Kühni Boghenbor Kathrin, Stoffel Michael H, Syring Claudia, Meylan Mireille, Müller Simone, Müller Mathias, Gredler Birgit, Sölkner Johann, Leeb Tosso
Abstract excerpt
Tyrolean Grey cattle represent a local breed with a population size of ∼5000 registered cows. In 2003, a previously unknown neurological disorder was recognized in Tyrolean Grey cattle. The clinical signs of the disorder are similar to those of bovine progressive degenerative myeloencephalopathy (weaver syndrome) in Brown Swiss cattle but occur much earlier in life. The neuropathological investigation of an...
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