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Article

A mitochondrial GABA permease connects the GABA shunt and the TCA cycle, and is essential for normal carbon metabolism.

The Plant journal : for cell and molecular biology - 1 Aug 2011

Michaeli Simon, Fait Aaron, Lagor Kelly, Nunes-Nesi Adriano, Grillich Nicole, Yellin Ayelet, Bar Dana, Khan Munziba, Fernie Alisdair R, Turano Frank J, Fromm Hillel

Abstract excerpt

In plants, γ-aminobutyric acid (GABA) accumulates in the cytosol in response to a variety of stresses. GABA is transported into mitochondria, where it is catabolized into TCA cycle or other intermediates. Although there is circumstantial evidence for mitochondrial GABA transporters in eukaryotes, none have yet been identified. Described here is an Arabidopsis protein similar in sequence and topology to...

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PMID: 21501262
DOI: 10.1111/j.1365-313X.2011.04612.x

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