Article
Sex modulation of the occurrence of jak2 v617f mutation in patients with splanchnic venous thrombosis.
Thrombosis research - 1 Sept 2011
Colaizzo Donatella, Tiscia Giovanni Luca, Bafunno Valeria, Amitrano Lucio, Vergura Patrizia, Lupone Maria Rosaria, Grandone Elvira, Guardascione Maria Anna, Margaglione Maurizio
Abstract excerpt
BACKGROUND: The JAK2 V617F mutation is an independent risk factor for MPN and SVT. Gender-related differences in MPN distribution have been reported and, recently, variability in the JAK2 V617F allele burden between sexes has been suggested. We wondered whether gender would modulate the role of the JAK2 V617F mutation as susceptibility risk factor for SVT. MATERIALS AND METHODS: In 180 patients presenting with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.