Article
Unstable maternal environment, separation anxiety, and heightened CO2 sensitivity induced by gene-by-environment interplay.
PloS one - 8 Apr 2011
D'Amato Francesca R, Zanettini Claudio, Lampis Valentina, Coccurello Roberto, Pascucci Tiziana, Ventura Rossella, Puglisi-Allegra Stefano, Spatola Chiara A M, Pesenti-Gritti Paola, Oddi Diego, Moles Anna, Battaglia Marco
Abstract excerpt
BACKGROUND: In man, many different events implying childhood separation from caregivers/unstable parental environment are associated with heightened risk for panic disorder in adulthood. Twin data show that the occurrence of such events in childhood contributes to explaining the covariation between separation anxiety disorder, panic, and the related psychobiological trait of CO(2) hypersensitivity. We...
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