Article
Alanine 32 in PilA is important for PilA stability and type IV pili function in Myxococcus xanthus.
Microbiology (Reading, England) - 1 Jul 2011
Yang Zhe, Hu Wei, Chen Kevin, Wang Jing, Lux Renate, Zhou Z Hong, Shi Wenyuan
Abstract excerpt
Type IV pili (TFP) are membrane-anchored filaments with a number of important biological functions. In the model organism Myxococcus xanthus, TFP act as molecular engines that power social (S) motility through cycles of extension and retraction. TFP filaments consist of several thousand copies of a protein called PilA or pilin. PilA contains an N-terminal α-helix essential for TFP assembly and a C-terminal...
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