Article
Human cytomegalovirus glycoprotein B genotyping from bronchoalveolar lavage specimens.
Canadian journal of microbiology - 1 Apr 2011
Bergallo Massimiliano, Costa Cristina, Gambarino Stefano, Tornicelli Alessandra, Astegiano Sara, Terlizzi Maria Elena, Solidoro Paolo, Cavallo Rossana
Abstract excerpt
The genes encoding glycoprotein complexes of human cytomegalovirus are often polymorphic; in particular, glycoprotein B (gB), which is essential for both in vivo and in vitro replication, is encoded by the highly polymorphic gene UL55. In this study, the distribution of gB genotypes was investigated in 44 bronchoalveolar lavage specimens from adult patients positive for human cytomegalovirus DNA by a multiplex...
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