Secondary recurrent miscarriage and H-Y immunity

Abstract excerpt

BACKGROUND: Approximately half recurrent miscarriage (RM) cases remain unexplained after standard investigations. Secondary RM (SRM) is, in contrast to primary RM, preceded by a birth, which increases the transfer of fetal cells into the maternal circulation. Mothers of boys are often immunized against male-specific minor histocompatibility (H-Y) antigens, and H-Y immunity can cause graft-versus-host disease...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Hematopoietic Stem Cell Transplantation
• Share to Prenatal Screening and Diagnostics
• Share to Reproductive System and Pregnancy