Article
Adherence and genotypic drug resistance mutations in HIV-1-infected patients failing current antiretroviral therapy.
Journal of chemotherapy (Florence, Italy) - 1 Feb 2011
d'Ettorre G, Forcina G, Ceccarelli G, Andreotti M, Andreoni C, Rizza C, Massetti A P, Sarmati L, Mastroianni C M, Vella S, Andreoni M, Vullo V
Abstract excerpt
The aim of this study was to assess the correlation between the estimated adherence of HIV-1 infected patients with antiretroviral (ARV) therapy failure and drug-resistant mutations. We studied 40 patients with virological and immunological ARV-therapy failure. In order to assess the adherence of patients we used the SERAD questionnaire. Genomic sequencing of the HIV-1 pol gene was performed. 100% adherence was...
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