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Article

Novel IRF6 mutations in Honduran Van der Woude syndrome patients.

Molecular medicine reports - 1 Jan 2000

Birkeland Andrew C, Larrabee Yuna, Kent David T, Flores Carlos, Su Gloria H, Lee Joseph H, Haddad Joseph

Abstract excerpt

Van der Woude syndrome (VWS) is an autosomal dominant inherited disease characterized by lower lip pits, cleft lip and/or cleft palate. Missense, nonsense and frameshift mutations in IRF6 have been revealed to be responsible for VWS in European, Asian, North American and Brazilian populations. However, the mutations responsible for VWS have not been studied in Central American populations. Here, we investigated...

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Identifiers

PMID: 21468557
DOI: 10.3892/mmr.2011.423

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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