Article
Embryonic signaling in melanoma: potential for diagnosis and therapy.
Laboratory investigation; a journal of technical methods and pathology - 1 Jun 2011
Strizzi Luigi, Hardy Katharine M, Kirsammer Gina T, Gerami Pedram, Hendrix Mary J C
Abstract excerpt
As the frequency of melanoma diagnosis increases, current treatment strategies are still struggling to significantly impact patient survival. Some promise has been shown in treating certain melanomas by targeting activated signaling pathways resulting from specific mutations in proteins, such as BRAF and NRAS. Recently, the identification of embryonic signaling pathways in melanoma has helped us better understand...
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