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Article

Selective breeding for susceptibility to myopia reveals a gene-environment interaction.

Investigative ophthalmology & visual science - 8 Jun 2011

Chen Yen-Po, Hocking Paul M, Wang Ling, Povazay Boris, Prashar Ankush, To Chi-Ho, Erichsen Jonathan T, Feldkaemper Marita, Hofer Bernd, Drexler Wolfgang, Schaeffel Frank, Guggenheim Jeremy A

Abstract excerpt

Purpose. To test whether the interanimal variability in susceptibility to visually induced myopia is genetically determined. Methods. Monocular deprivation of sharp vision (DSV) was induced in outbred White Leghorn chicks aged 4 days. After 4 days' DSV, myopia susceptibility was quantified by the relative changes in axial length and refraction. Chicks in the extreme tails of the distribution of susceptibility to...

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PMID: 21436268
DOI: 10.1167/iovs.10-7044

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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