Article
Manufacture of clinical grade human placenta-derived multipotent mesenchymal stromal cells.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2011
Ilic Nina, Brooke Gary, Murray Patricia, Barlow Sarah, Rossetti Tony, Pelekanos Rebecca, Hancock Sonia, Atkinson Kerry
Abstract excerpt
Clinical grade human mesenchymal stem cells (MSC) are manufactured and used in clinical trials for a range of regenerative and inflammatory diseases. Human MSC have now been derived from tissues other than bone marrow, such as placenta, as described in this laboratory protocol. It provides instructions for clinical grade MSC manufacturing according to the Code of Good Manufacturing Practice (cGMP) principles and...
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