Article
Utilizing twins concordance rates to infer the predisposition to myasthenia gravis.
Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Apr 2011
Ramanujam Ryan, Pirskanen Ritva, Ramanujam S, Hammarström Lennart
Abstract excerpt
Myasthenia gravis (MG) is an autoimmune disorder in which patients experience muscular fatigability due to the presence of anti-acetylcholine receptor (AChR) antibodies which inhibit signal transduction across the neuro-muscular junction. Like all complex disorders, disease is caused by an interaction between genetic and environmental factors. Although several genes have been identified which appear to be...
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