Article
[Epigentics in rheumatic diseases].
Zeitschrift fur Rheumatologie - 1 Apr 2011
Jüngel A, Gay S
Abstract excerpt
The human genome comprises approximately 30000 genes needed for the formation and function of approximately 1 Million proteins in the human body. Differentiation leads to the deactivation of genes that are not needed in the specific tissues or cells. To regulate the cell specific gene expression in normal cells epigenetic modifications work in concert with genetic mechanisms. In contrast to genetic mutations,...
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