[One example of false negative hepatitis B surface antigen (EIA) result due to variant S area strain and reagment reactiveness related to hepatitis B surface antigen].

doi:10.11150/kansenshogakuzasshi.85.21

Article

[One example of false negative hepatitis B surface antigen (EIA) result due to variant S area strain and reagment reactiveness related to hepatitis B surface antigen].

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases - 1 Jan 2011

Matsuda Chikashi, Moriyama Hidehiko, Taketani Takeshi, Shibata Hiroshi, Nagai Atsushi

Abstract excerpt

The presence in serum of the Hepatitis B surface antigen (HBsAg), the outer envelope of the hepatitis B virus (HBV), indicates viral infection, used in laboratory tests to confirm this. We report a case of discrepancy among HBsAg test results detected between measurements in a subject with HB infection. Gene analysis demonstrated several S region gene mutations, not detected previously. We tested 12 measurements...

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[One example of false negative hepatitis B surface antigen (EIA) result due to variant S area strain and reagment reactiveness related to hepatitis B surface antigen].

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