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Article

A macrophage and theca cell-enriched stromal cell population influences growth and survival of immature murine follicles in vitro.

Reproduction (Cambridge, England) - 1 Jun 2011

Tingen Candace M, Kiesewetter Sarah E, Jozefik Jennifer, Thomas Cristina, Tagler David, Shea Lonnie, Woodruff Teresa K

Abstract excerpt

Innovations in in vitro ovarian follicle culture have revolutionized the field of fertility preservation, but the successful culturing of isolated primary and small secondary follicles remains difficult. Herein, we describe a revised 3D culture system that uses a feeder layer of ovarian stromal cells to support early follicle development. This culture system allows significantly improved primary and early...

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Identifiers

PMID: 21389078
DOI: 10.1530/REP-10-0483
PMCID: PMC4077622

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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