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Article

Nonlesional atopic dermatitis skin is characterized by broad terminal differentiation defects and variable immune abnormalities.

The Journal of allergy and clinical immunology - 1 Apr 2011

Suárez-Fariñas Mayte, Tintle Suzanne J, Shemer Avner, Chiricozzi Andrea, Nograles Kristine, Cardinale Irma, Duan Shenghui, Bowcock Anne M, Krueger James G, Guttman-Yassky Emma

Abstract excerpt

BACKGROUND: Atopic dermatitis (AD) is a common inflammatory skin disease with a T(H)2 and "T22" immune polarity. Despite recent data showing a genetic predisposition to epidermal barrier defects in some patients, a fundamental debate still exists regarding the role of barrier abnormalities versus immune responses in initiating the disease. An extensive study of nonlesional AD (ANL) skin is necessary to explore...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 21388663
DOI: 10.1016/j.jaci.2010.12.1124
PMCID: PMC3128983

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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